TY - CHAP M1 - Book, Section TI - Principles for the Practice of Clinical Genetics A1 - Eble, Tanya N. A1 - Nagamani, Sandesh C. S. A2 - Kline, Mark W. Y1 - 2018 N1 - T2 - Rudolph's Pediatrics, 23e AB - Few specialties of medicine, if any, can match the unprecedented advances that have occurred in the field of human and medical genetics during the last 2 decades. Since completion of the sequencing of the human genome in 2003, our understanding of the genetic bases of rare single-gene disorders as well as common multifactorial disorders has increased tremendously. Molecular cytogenetic and sequencing techniques are not only being widely used for diagnosis of many disorders but also to help guide management and therapy, particularly cancer therapy. This chapter outlines the key principles of genetics that are relevant for the practice of medicine. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/05 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182930509 ER -