TY - CHAP M1 - Book, Section TI - Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis A1 - Jethva, Reena A1 - Treat, James R. A2 - Zaoutis, Lisa B. A2 - Chiang, Vincent W. Y1 - 2017 N1 - T2 - Comprehensive Pediatric Hospital Medicine, 2e AB - Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous reactions that are best considered part of the same disease process. SJS and TEN are idiosyncratic reactions, typically to medications or infections, characterized by cutaneous epidermal skin necrosis along with involvement of at least two mucous membranes. In the past, erythema multiforme (EM, see Chapter 64) was classified into minor and major forms, the major form being synonymous with SJS. However, it is now recognized that despite histologic similarities, SJS and EM are best regarded as separate entities with distinct clinical presentations, outcomes, and causes.1 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1146115938 ER -