TY - CHAP M1 - Book, Section TI - Pneumothorax and Pneumomediastinum A1 - Nagler, Joshua A2 - Zaoutis, Lisa B. A2 - Chiang, Vincent W. Y1 - 2017 N1 - T2 - Comprehensive Pediatric Hospital Medicine, 2e AB - Pneumothorax and pneumomediastinum are examples of air leak syndromes in which air accumulates in the spaces outside the lung airways and alveoli. Pneumothorax refers to the abnormal presence of air in the pleural space, whereas pneumomediastinum describes accumulation of air in the mediastinum. Air leak can be traumatic, iatrogenic, or spontaneous. Primary air leak occurs in children without clinically apparent lung disease, and secondary pneumomediastinum and pneumothorax refer to those with known underlying pulmonary disease (e.g. asthma, cystic fibrosis). Air leak secondary to barotrauma from positive-pressure ventilation or after surgery is commonly categorized as iatrogenic. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/23 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1146123459 ER -