TY  - CHAP
M1  - Book, Section
TI  - Varicella-Zoster Virus Infections
A1  - Poole, Claudette L.
A1  - Kimberlin, David W.
A2  - Kline, Mark W.
Y1  - 2018
N1  - 
T2  - Rudolph's Pediatrics, 23e
AB  - Varicella-zoster  virus  (VZV)  is  1  of  the  9  human  herpesviruses,  which  include  herpes  simplex  virus  (HSV)  types  1  and  2,  cytomegalovirus,  Epstein-Barr  virus,  and  human  herpesviruses  6A,  6B,  7,  and  8.  As  with  HSV-1  and  HSV-2,  VZV  establishes  latency  in  sensory  or  autonomic  ganglia  following  primary  infection,  with  the  ability  for  subsequent  reactivation.  The  primary  acquisition  of  VZV  results  in  the  clinical  disease  varicella  (chickenpox)  with  reactivation  from  latency  resulting  in  zoster  (shingles).  Live-attenuated  varicella  vaccine  was  licensed  in  the  United  States  in  1995  and,  over  the  past  20  years,  has  substantially  altered  the  epidemiology  of  the  disease  in  this  country,  with  rates  of  varicella  and  its  complications  plummeting.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/18
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=1182903470
ER  -