TY - CHAP M1 - Book, Section TI - Lymphatic Filariasis and Onchocerciasis A1 - Dulek, Daniel E. A2 - Kline, Mark W. Y1 - 2018 N1 - T2 - Rudolph's Pediatrics, 23e AB - Filarial worms are parasitic nematodes that dwell within the lymphatics and the subcutaneous tissues. Eight filarial species are associated with human disease, though only 4 cause significant morbidity in children (Table 323-1). These species include the causative agents of lymphatic filariasis—Wuchereria bancrofti, Brugia malayi, and Brugia timori—and Onchocerca volvulus, the causative agent of onchocerciasis. The filarial parasites can be distinguished by their geographic distribution, vector, anatomic location of adult worms, and anatomic location and periodicity of microfilaria detection. Of the human filarial parasites, W bancrofti is, by far, the most important in terms of both morbidity and numbers of people infected. O volvulus remains an important cause of worldwide morbidity, especially in Africa. With elimination of O volvulus from selected transmission zones in the Americas, there is hope of eventual elimination from Africa. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182903974 ER -