TY - CHAP M1 - Book, Section TI - Neonatal Dermatology A1 - Diaz, Lucia Z. A1 - Levy, Moise L. A2 - Kline, Mark W. Y1 - 2018 N1 - T2 - Rudolph's Pediatrics, 23e AB - The skin of a newborn infant differs from adult skin in several ways that place infants at increased risk for thermal instability, skin damage, percutaneous infection, and percutaneous toxicity from topically applied agents. The neonatal body surface area–to–weight ratio is far greater than that of an adult with thinner skin overall. Sebaceous glands are hypertrophic for several weeks after birth, under the influence of fetal and maternal androgens, but eccrine function does not mature until after term, placing newborns at risk for hyperthermia with overbundling. The vernix caseosa is composed of sloughed keratinocyte and sebaceous gland lipids, with a higher proportion of glandular lipids in males. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182905035 ER -