TY - CHAP M1 - Book, Section TI - Malaria A1 - John, Chandy C. A2 - Kline, Mark W. Y1 - 2018 N1 - T2 - Rudolph's Pediatrics, 23e AB - Malaria is among the leading infectious causes of morbidity and mortality in children worldwide. Each year, there are more than 200 million clinical cases, causing an estimated 438,000 deaths in 2015, most in sub-Saharan African children under the age of 5 years. Increasing drug resistance, climatic changes, population shifts, economic changes, abandonment of malaria control programs, and insecticide resistance all contributed to a resurgence of malaria in the developing world from the 1970s to the 2000s. Recent World Health Organization (WHO), governmental, and nonprofit foundation support for effective preventative measures—such as insecticide-treated bednets, indoor residual spraying, and the implementation of artemisinin combination therapy as first-line treatment for malaria in many sub-Saharan African countries—has significantly reduced malaria incidence and deaths in many countries. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182904730 ER -