TY - CHAP M1 - Book, Section TI - Gastrointestinal Disorders Associated with Immunodeficiency A1 - Noel, Richard J. A2 - Kline, Mark W. Y1 - 2018 N1 - T2 - Rudolph's Pediatrics, 23e AB - Children with primary or acquired immunodeficiency are at increased risk for gastrointestinal (GI) infection or immune-related mucosal inflammation. The risk and severity of infection depends on the type of immunodeficiency; patients with deficiencies of antibody response are predisposed to extracellular bacterial infections and intestinal pathogens, and those with deficiencies of T cells are predisposed to both intracellular and extracellular infections. Patients with primary immunodeficiency are also more likely to develop autoimmune disorders, often affecting the GI tract. Conversely, those patients who present with various features of pediatric autoimmune enteropathy frequently can be found to have immunodeficiency disorders. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/11/13 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182907452 ER -