TY - CHAP M1 - Book, Section TI - Disorders of the Exocrine Pancreas A1 - Lin, Tom K. A1 - Abu-El-Haija, Maisam A1 - Palermo, Joseph J. A2 - Kline, Mark W. Y1 - 2018 N1 - T2 - Rudolph's Pediatrics, 23e AB - In the fourth week of gestation, the human pancreas develops as 2 outpouchings of the duodenal endoderm. The larger dorsal bud develops into the tail, body, and a portion of the head of the pancreas. The ventral bud fuses with the dorsal bud at about the 17th week of gestation to create the remainder of the head of the pancreas and the uncinate process. Each bud possesses its own ductal system; variations in fusion, which occur in 15% of the population, lead to developmental anomalies. These anatomic anomalies of the pancreas may be normal variants or result in symptomatic pathologic disease. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182908834 ER -