TY - CHAP M1 - Book, Section TI - Acute Respiratory Distress Syndrome A1 - Rozenfeld, Ranna A. Y1 - 2018 N1 - T2 - The PICU Handbook AB - Acute inflammation occurring as a result of either direct or indirect injuryHallmark of acute phase is diffuse alveolar damage via altered permeability of pulmonary endothelial and epithelial cellsLeads to accumulation of protein-rich fluid in alveoliInactivates surfactantLeads to hypoxia and impaired lung compliance SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1152487703 ER -