TY - CHAP M1 - Book, Section TI - Neonatal Hemodynamics A1 - Evans, Nicholas A2 - Kline, Mark W. Y1 - 2018 N1 - T2 - Rudolph's Pediatrics, 23e AB - Hemodynamics, or the movement of blood, is necessary to delivery oxygen to the tissues of the body. Oxygen delivery is determined by several factors, and failure of any these can lead to organ injury and/or death. Oxygen delivery is determined by (1) the oxygen level and carrying capacity of the blood, both of which are easy to measure and monitor and (2) the flow rate of blood around the systemic and pulmonary circulations. Both the circulations are driven by the heart, and the flow is measured by the output of each of the ventricles. In a mature circulation, the right ventricular output (RVO) drives the pulmonary blood flow and the left ventricular output (LVO) drives the systemic blood flow. The efficiency with which each ventricle does this is determined by the volume of blood entering the ventricle (the preload), the health (or maturity) of the myocardium (contractility), and the resistance against which the ventricle is pumping (afterload). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182921383 ER -