TY - CHAP M1 - Book, Section TI - Nonsteroidal Anti-Inflammatory Drugs A1 - Lowry, Jennifer A. A2 - Tenenbein, Milton A2 - Macias, Charles G. A2 - Sharieff, Ghazala Q. A2 - Yamamoto, Loren G. A2 - Schafermeyer, Robert Y1 - 2019 N1 - T2 - Strange and Schafermeyer's Pediatric Emergency Medicine, 5e AB - Nonsteroidal anti-Inflammatory drugs (NSAIDs) are relatively devoid of toxicity in the overdose setting.Patients who develop toxicity exhibit central nervous system or gastrointestinal signs and symptoms.Overdose of NSAIDs has been associated with an anion-gap acidosis.Long-term use of NSAIDs is associated with nephrotoxicity, including acute tubular necrosis, acute interstitial nephritis, and acute renal failure. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1155748612 ER -