TY - CHAP M1 - Book, Section TI - Canavan Disease (CD) A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas Y1 - 2019 N1 - T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - A progressive leukodystrophy caused by spongy degeneration of the central nervous system. The clinical triad of hypotonia, macrocephaly, and lack of head control in an infant more than 3 to 5 months old should raise suspicion for this disorder. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/11/04 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1164064288 ER -