TY - CHAP M1 - Book, Section TI - Gangliosidosis (GM2) Type II A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas Y1 - 2019 N1 - T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - Heritable lysosomal storage disorder with ganglioside accumulation leading to severe neurologic impairment with premature death. Tay-Sachs disease (TSD) and its variants are caused by absence or defects of the alpha subunit of hexosaminidase A. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1164070526 ER -