TY - CHAP M1 - Book, Section TI - Happy Puppet Syndrome A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas Y1 - 2019 N1 - T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - The Happy Puppet Syndrome (Angelman’s Syndrome) is a genetic disorder that mainly affects the nervous system. The clinical features include microcephaly, happy facial appearance, severe mental retardation, developmental disability, speech problems (absence of speech), balance and movement problems, seizures, and sleep problems and social disposition. Children are usually happy in nature and have a particular interest in water. The symptoms generally become noticeable by 1 year of age. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1164072081 ER -