TY - CHAP M1 - Book, Section TI - Hemoglobin C Disease A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas Y1 - 2019 N1 - T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - Genetically inherited hemolytic anemia, usually mild and often inapparent until adulthood. This disease is mainly encountered in populations of African descent, but also in populations of Sicilian and Hispanic descent. Hemoglobin C (Hb C) is one of the most common structural hemoglobin variants in the human population. Persons with hemoglobin C trait (Hb AC) are phenotypically normal, with no clinically evident limitations or symptoms, while those with Hemoglobin C Disease (Hb C) may have a mild degree of hemolytic anemia, splenomegaly, and borderline anemia. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/08 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1164072336 ER -