TY - CHAP M1 - Book, Section TI - Holt-Oram Syndrome (HOS) A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas Y1 - 2019 N1 - T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - Genetically transmitted malformation syndrome characterized by congenital anomalies of the upper extremity malformations involving radial, thenar (hypoplasia or triphalangeal thumb), or carpal bones associated with heart disease (ventricular and atrial septal defect as well as conduction problems). This medical condition can also affect other part of the skeletal structure. It is reported that approximately 75% of individuals with Holt-Oram Syndrome have severe heart problems. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1164073080 ER -