TY - CHAP M1 - Book, Section TI - Pyruvate Carboxylase Deficiency A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas Y1 - 2019 N1 - T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - Rare mitochondrial disease leading to hypoglycemia and severe lactic acidosis. Clinically characterized by seizures, neuromuscular incoordination, abnormal eye movements, and poor response to visual stimuli. Other clinical features include lethargy, vomiting, and poor feeding. Apnea, dyspnea and/or respiratory depression complete the presentation. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1164082968 ER -