TY - CHAP M1 - Book, Section TI - Thrombotic Thrombocytopenic Purpura (TTP) A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas Y1 - 2019 N1 - T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - Systemic disease characterized by platelet aggregation into widespread platelet thrombi and resulting occlusion of the microvasculature. This disease is closely related to and overlaps with Hemolytic Uremic Syndrome (HUS) within the broader definition of thrombotic microangiopathies. Clinical features include seizure, hemiplegia, fatigue, abdominal pain, arthralgias, neurological deficit, and renal insufficiency. Idiopathic presentation with a 60% female preponderance. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1164086415 ER -