TY  - CHAP
M1  - Book, Section
TI  - Hyperbilirubinemia: Unconjugated, On Call
A1  - Gomella, Tricia Lacy
A1  - Eyal, Fabien G.
A1  - Bany-Mohammed, Fayez
Y1  - 2020
N1  - 
T2  - Gomella's Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 8e
AB  - An  infant’s  indirect  (unconjugated)  serum  bilirubin  level  is  elevated  at  10  mg/dL.  Unconjugated  (indirect)  bilirubin  is  the  fraction  of  serum  bilirubin  that  has  not  been  conjugated  with  glucuronic  acid  in  the  liver.  The  exact  definition  of  a  physiologic  range  and  management  of  indirect  hyperbilirubinemia  are  complex  and  based  on  many  factors,  including  gestational  age  (GA),  postnatal  age,  birthweight,  disease  state,  risk  factors,  ethnicity,  and  hydration  and  nutritional  status.  Total  serum  bilirubin  (TSB)  is  the  sum  of  direct  (conjugated)  and  indirect  (unconjugated)  bilirubin.  The  indirect  bilirubin  is  calculated  by  subtracting  the  direct  bilirubin  from  the  total  bilirubin.  Transcutaneous  bilirubin  (TcB)  is  a  measurement  of  TSB  from  an  instrument  that  uses  reflectance  measurements  on  the  skin  and  correlates  well  with  the  laboratory  TSB  value.  Unconjugated  hyperbilirubinemia  is  usually  transient  and  physiologic  in  the  newborn  period,  but  it  is  important  to  note  that  kernicterus  (chronic  bilirubin  encephalopathy)  is  still  occurring  in  the  developed  world.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/20
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=1168356811
ER  -