TY - CHAP M1 - Book, Section TI - Rh Incompatibility A1 - Gomella, Tricia Lacy A1 - Eyal, Fabien G. A1 - Bany-Mohammed, Fayez Y1 - 2020 N1 - T2 - Gomella's Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 8e AB - Rh incompatibility is a condition that occurs during pregnancy when a mother with Rh-negative blood [who is previously sensitized to the Rh(D) antigen] is exposed to her fetus who is Rh-positive leading to the development of Rh antibodies and resulting in fetal isoimmune hemolytic anemia of variable severity. The onset of clinical disease begins in utero as the result of active placental transfer of maternal immunoglobulin (Ig)G-Rh antibody. It is manifested as a partially compensated, moderate to severe hemolytic anemia at birth, with unconjugated hyperbilirubinemia developing in the early neonatal period. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/20 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1168358267 ER -