TY - CHAP M1 - Book, Section TI - Immunodeficiency A1 - Abbott, Jordan K. A1 - Hauk, Pia J. A2 - Hay Jr., William W. A2 - Levin, Myron J. A2 - Abzug, Mark J. A2 - Bunik, Maya Y1 - 2020 N1 - T2 - Current Diagnosis & Treatment: Pediatrics, 25e AB - Immune deficiencies that present in childhood comprise rare disorders that have been characterized by a combination of clinical patterns, immunologic laboratory tests, and often molecular identification of the mutant gene. Children with Primary Immunodeficiency (PID) commonly present with recurrent and/or severe bacterial infections, failure to thrive, and/or developmental delay as a result of infection. Immunodeficiency should be considered when infections are recurrent, severe, persistent, resistant to standard treatment, or caused by opportunistic organisms. Because delayed diagnosis of PIDs is common, heightened diagnostic suspicion is warranted. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1172111145 ER -