TY - CHAP M1 - Book, Section TI - Myasthenia Gravis and Related Disorders of the Neuromuscular Junction A1 - Zygmunt, Alexander M. A1 - Tian, Cuixia A2 - Hershey, Andrew D. Y1 - 2023 N1 - T2 - CURRENT Diagnosis & Treatment Pediatric Neurology AB - Pediatric disorders of the neuromuscular junction (NMJ), a group of disorders that affect the structure, function, or both the structure and function of the NMJ, can be acquired or congenital. Patients with NMJ disorders typically present with weakness that fluctuates throughout the day and is fatigable in nature. Classically, fluctuating weakness affects extraocular musculature early in the disease course, causing symptoms such as fluctuating ptosis or diplopia. Bulbar weakness is also commonly described in NMJ disorders, which can present as difficulty swallowing, choking, gagging, weak crying, nasal-sounding voice, or neck flexion or extension weakness. SN - PB - McGraw Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1195238413 ER -