TY - CHAP M1 - Book, Section TI - Chapter 197. Adverse Reactions to Drugs A1 - Riedel, Marc A. A2 - Rudolph, Colin D. A2 - Rudolph, Abraham M. A2 - Lister, George E. A2 - First, Lewis R. A2 - Gershon, Anne A. Y1 - 2011 N1 - T2 - Rudolph's Pediatrics, 22e AB - Drug reactions encompass all adverse events related to drug administration, regardless of etiology.1 While adverse drug reactions are common, only a small portion of these represent drug hypersensitivity, defined as an immunologically-mediated response to a drug agent in a sensitized patient. In turn, only a subset of drug hypersensitivity reactions represent a true drug allergy, which refers specifically to a reaction mediated by IgE.2 These distinctions are important for optimal patient management, risk assessment, and education of patients regarding specific drug reactions. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=7018791 ER -