TY  - CHAP
M1  - Book, Section
TI  - Chapter 223. Bacteremia, Sepsis, and Septic Shock
A1  - Stovall, Stephanie H.
A1  - Jacobs, Richard F.
A2  - Rudolph, Colin D.
A2  - Rudolph, Abraham M.
A2  - Lister, George E.
A2  - First, Lewis R.
A2  - Gershon, Anne A.
Y1  - 2011
N1  - 
T2  - Rudolph's Pediatrics, 22e
AB  - Children  presenting  with  pathogenic  bacteria  in  a  blood  culture  (bacteremia)  manifest  a  wide  spectrum  of  clinical  signs  and  symptoms.  The  continuum  from  bacteremia  to  sepsis,  severe  sepsis,  and  septic  shock  depends  on  a  complex  series  of  interrelated  factors  that  include  the  specific  etiology,  the  inoculum  of  organisms,  strain  variations  or  virulence  factors,  extracellular  components  or  toxin  production,  the  site  of  infection,  the  immunologic  competence  of  the  host,  and  the  host  response  to  the  infection.  Bacteremia  may  be  occult,  a  transient  phenomenon  not  associated  with  a  specific  focus  of  infection,  or  it  may  result  from  the  extension  of  an  invasive  bacterial  infection  originating  in  the  genitourinary,  gastrointestinal,  upper  or  lower  respiratory  tracts,  or  skin  and  soft  tissues.  Specific  secondary  infection  (meningitis,  osteomyelitis,  pyelonephritis,  peritonitis,  intra-abdominal  abscess,  or  facial  cellulitis)  may  also  occur  and  affect  management.  Recurrent  or  persistent  bacteremia  may  result  from  established  infectious  foci  (endocarditis,  abscess,  foreign-body  infection).  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=7021160
ER  -