TY - CHAP M1 - Book, Section TI - Chapter 354. Toxoplasmosis A1 - Saux, Nicole M. A. Le A2 - Rudolph, Colin D. A2 - Rudolph, Abraham M. A2 - Lister, George E. A2 - First, Lewis R. A2 - Gershon, Anne A. Y1 - 2011 N1 - T2 - Rudolph's Pediatrics, 22e AB - It is estimated that 500 million people worldwide are infected with Toxoplasma gondii.1 Seroprevalence studies have uniformly indicated increasing rates with age (eFig. 354.1). Between 1999 and 2004, the age-adjusted T. gondii seroprevalence rate declined from 14.1% to 9% among U.S.-born persons ages 12 to 49 years.2 The rates varied among regions, probably due to differing climates, culinary practices, and immigration patterns from areas of the world that have higher endemic rates of Toxoplasma infections. Data from Europe generally indicates a slightly higher prevalence rate compared to the United States, with rates in Central Europe ranging from 24% in Greece to 41% in France and Poland.3-5 In the United States, seroprevalence rates in women of childbearing age are approximately 15%, whereas rates in similar populations from western Europe, Africa, and Central and South America are greater than 50%.1,6 The general population of blood donors from Turkey was found to have a 20% seroprevalence rate, while the seroprevalence restricted to women was found to be relatively high at 52.1%.7,8 In the last two decades, most European countries have noted a decrease in seroprevalence of Toxoplasma, possibly due to less infection in farm animals, more filtration of drinking water, and concerns about consuming undercooked meat. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/23 UR - accesspediatrics.mhmedical.com/content.aspx?aid=7032232 ER -