TY - CHAP M1 - Book, Section TI - Chapter 505. Clinical Presentation of Respiratory Illness A1 - Pasterkamp, Hans A2 - Rudolph, Colin D. A2 - Rudolph, Abraham M. A2 - Lister, George E. A2 - First, Lewis R. A2 - Gershon, Anne A. Y1 - 2011 N1 - T2 - Rudolph's Pediatrics, 22e AB - Respiratory illness in children usually presents with clinical symptoms and signs that offer important information for further diagnostic tests. The primary function of the respiratory system is to provide a supply of oxygen and removal of carbon dioxide, that is, adequate and adaptive gas exchange. Illness can disturb this function by affecting respiratory control, the respiratory pump, that is, chest cage and respiratory muscles, airways, and the pulmonary tissues. The many nonrespiratory functions of the lung include production and regulation of surfactant, defense against infections, participation in water and fluid balance, sieving of blood cells and emboli, and elimination of volatile substances. The clinical presentation of illness interfering with these functions is often related to the secondary effects on respiratory mechanics and gas exchange. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/16 UR - accesspediatrics.mhmedical.com/content.aspx?aid=7050182 ER -