TY  - CHAP
M1  - Book, Section
TI  - Chapter 524. Tall Stature
A1  - Reiter, Edward O.
A2  - Rudolph, Colin D.
A2  - Rudolph, Abraham M.
A2  - Lister, George E.
A2  - First, Lewis R.
A2  - Gershon, Anne A.
Y1  - 2011
N1  - 
T2  - Rudolph's Pediatrics, 22e
AB  - Most  tall  children  are  normal,  and  their  stature  is  linked  to  genetic  background  and  an  optimal  environment  for  growth.  Tall  stature  is  concerning  only  if  a  child’s  tallness  is  inappropriate  for  parental  height  or  when  linear  growth  velocity  accelerates  inappropriately.  A  number  of  endocrine  and  nonendocrine  disorders  cause  excessive  linear  growth  during  childhood  and  adolescence  (Table  524-1).  Endocrine  causes  of  accelerated  growth  include  growth  hormone  (GH)  excess  or  acromegaly;  thyrotoxicosis;  excess  androgenic  hormones,  as  in  congenital  adrenal  hyperplasia  and  virilizing  tumors;  and  sexual  precocity.  The  latter  disorders  are  readily  apparent  on  physical  examination  because  of  accompanying  signs  of  androgen  excess  or  sexual  maturation.  Adolescents  with  hypogonadotropic  hypogonadism  can  also  be  tall  and  have  a  eunuchoid  habitus.  Other  clinical  entities  that  can  cause  an  increase  in  absolute  height  or  accelerated  height  velocity  include  obesity,  Marfan  syndrome,  homocystinuria,  total  lipodystrophy,  neurofibromatosis,  and  chromosomal  abnormalities  such  as  Klinefelter  syndrome,  and  48XXYY  and  47XYY  syndromes.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/16
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=7053055
ER  -