TY - CHAP M1 - Book, Section TI - Chapter 31. Acute and Chronic Pancreatitis A1 - Lowe, Mark E. A2 - Bishop, Warren P. Y1 - 2010 N1 - T2 - Pediatric Practice: Gastroenterology AB - Inflammatory disorders of the pancreas are classified as acute or chronic. Acute pancreatitis is generally a reversible process with no significant permanent effects on pancreatic histology or function, whereas chronic pancreatitis leads to irreversible changes in the architecture and function of the pancreas. Both are defined clinically. Acute pancreatitis is a distinct event requiring two of the following three features for diagnosis: (1) clinical symptoms consistent with acute pancreatitis, (2) serum amylase or lipase levels or both at least three times the upper limit of normal, and (3) findings of acute pancreatitis on transabdominal ultrasonography or on contrast-enhanced computed tomography (CECT). Chronic pancreatitis is a progressive disease leading to typical histological and morphological changes in the pancreas, usually identified by radiographic methods, or to loss of digestive function or both. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=55944129 ER -