TY - CHAP M1 - Book, Section TI - Chapter 13. Neonatal Jaundice in Low- and Middle-Income Countries A1 - Slusher, Tina M. A1 - Olusanya, Bolajoko O. A2 - Stevenson, David K. A2 - Maisels, M. Jeffrey A2 - Watchko, Jon F. Y1 - 2012 N1 - T2 - Care of the Jaundiced Neonate AB - For the most part, in the developed world, neonatal jaundice occurs without significant morbidity and/or mortality due to early diagnosis and treatment.1 However, most literature from low-middle-income countries (LMICs) suggests that it accounts for significant morbidity and mortality in contrast to that in the United States and developed world (Table 13-1).2–18 For example, based on limited population-based data available worldwide, severe neonatal jaundice is about 100-fold greater in Nigeria than in the developed world. In one of the few population-based studies from the developed world, Ebbesen et al.17 from Denmark reported that 24/100,000 neonates met exchange blood transfusion (exchange transfusion [ET]) criteria, while 9/100,000 developed acute bilirubin encephalopathy (ABE), in comparison to results from the only population-based study in Nigeria, in which Olusanya et al. reported 1860/100,000 infants had an EBT.19 Based on the limited data available, ABE is at least as common as tetanus as a cause of neonatal deaths in Nigeria, Kenya, and Pakistan,11,13,20–23 and likely in most LMICs often ranking as one of the top five causes of neonatal death.8,11,13,24 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/11/03 UR - accesspediatrics.mhmedical.com/content.aspx?aid=56324207 ER -