TY - CHAP M1 - Book, Section TI - Bleeding Disorders A1 - McCreight, Audra L. A1 - Wickiser, Jonathan E. A2 - Schafermeyer, Robert A2 - Tenenbein, Milton A2 - Macias, Charles G. A2 - Sharieff, Ghazala Q. A2 - Yamamoto, Loren G. Y1 - 2014 N1 - T2 - Strange and Schafermeyer's Pediatric Emergency Medicine, 4e AB - Aggressive treatment of hemophilia patients with head trauma is imperative as signs and symptoms of intracranial bleeding may be delayed. Even though initial imaging studies may be normal, factor replacement is indicated and careful monitoring of the patient is crucial to detect subtle changes in mental status.Patients with hemophilia and inhibitors remain challenging management cases and are best cared for in conjunction with a hematologist.Treatment of bleeding episodes in von Willebrand patients may include desmopressin (DDAVP), cryoprecipitate, or factor VIII concentrates rich in von Willebrand factor (vWf).Treatment options for ITP are based on the clinical severity of bleeding. Consultation with a hematologist is indicated for patients with bleeding complications or platelet counts <20,000. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1105686020 ER -