TY - CHAP M1 - Book, Section TI - Spontaneous Intestinal Perforation A1 - Gomella, Tricia Lacy A1 - Cunningham, M. Douglas A1 - Eyal, Fabien G. A1 - Tuttle, Deborah J. Y1 - 2013 N1 - T2 - Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 7e AB - A spontaneous intestinal perforation (SIP) is a single intestinal perforation typically involving the antimesenteric border of distal ileum, which usually occurs without a defined prodrome in extremely premature infants in the first 1–2 weeks of life. These infants usually have not been fed (or have received minimum feeds). At the area of perforation, focal hemorrhagic necrosis with well-defined margins is observed in contrast to ischemic and coagulative necrosis seen in necrotizing enterocolitis (NEC). The bowel proximal and distal to the perforation appears normal. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/11/02 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1107525091 ER -