TY - CHAP M1 - Book, Section TI - Common Multiple Congenital Anomaly Syndromes A1 - Gomella, Tricia Lacy A1 - Cunningham, M. Douglas A1 - Eyal, Fabien G. A1 - Tuttle, Deborah J. Y1 - 2013 N1 - T2 - Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 7e AB - A congenital anomaly is defined as a structural defect, present at birth and different from the norm. These anomalies can be further divided into major anomalies that require medical and surgical care (eg, congenital heart defect, cleft palate, meningomyelocele) and minor anomalies that do not have medical significance (eg, single palmar crease, epicanthal folds, fifth digit clinodactyly). Anomalies themselves can be classified based on the developmental process involved in their formation. Well-defined types of anomalies include malformations, deformations, disruptions, dysplasias, syndromes, associations, and sequences (Table 89–1). It is also important to understand that these may not be entirely mutually exclusive. Table 89–1 provides an overview of congenital anomalies that are associated with congenital heart disease, and Table 89–2 reviews the teratogens associated with some of these lesions. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1107528465 ER -