TY - CHAP M1 - Book, Section TI - Intracranial Neoplasms and Masses A1 - Wells, Robert G. Y1 - 2015 N1 - T2 - Diagnostic Imaging of Infants and Children AB - The central nervous system (CNS) is the site of origin for approximately 20% of pediatric cancers. CNS neoplasms are the second most common type of childhood tumors, after leukemia. The overall 5-year survival rate for pediatric CNS malignancies is 70%. The prevalence of brain tumors in children younger than 15 years of age is approximately 2.4 per 100,000. High-grade (World Health Organization [WHO] grade ≥3) CNS neoplasms in children include primitive neuroectodermal tumor (PNET), malignant germ cell tumors, grade III/IV astrocytoma, leukemia/lymphoma, esthesioneuroblastoma, and metastatic disease. Low-grade (WHO grade ≤2) tumors include juvenile pilocytic astrocytoma, grade II astrocytoma, germinoma, craniopharyngioma, meningioma, ganglioglioma, nonanaplastic ependymoma, acoustic neuroma, low-grade oligodendroglioma, and dysembryoplastic neuroepithelial tumor (DNET).1 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1148949704 ER -