TY  - CHAP
M1  - Book, Section
TI  - Management of Unconjugated Hyperbilirubinemia
A1  - Bhutani, Vinod K.
A2  - Stevenson, David K.
A2  - Cohen, Ronald S.
A2  - Sunshine, Philip
Y1  - 2015
N1  - 
T2  - Neonatology: Clinical Practice and Procedures
AB  - Reduction  of  elevated  or  increasing  unconjugated  (indirect)  bilirubin  levels,  measured  as  total  plasma  bilirubin  (TB)  or  transcutaneous  bilirubin  (TcB),  is  key  to  the  prevention  of  bilirubin  toxicity.  Preterm  and  sick  infants  are  at  increased  risk  for  hyperbilirubinemia  and  its  sequelae.  Factors  that  place  these  populations  at  risk  for  hyperbilirubinemia  include  impaired  bilirubin-albumin  binding,  decreased  enteral  intake,  and  decreased  gastrointestinal  activity,  resulting  in  increased  enterohepatic  circulation.  As  a  result  of  biological  conditions  such  as  vulnerability  of  the  blood-brain  barrier,  asphyxia,  acidosis,  and  hypoalbuminemia,  neurotoxicity  may  occur  at  lower  bilirubin  levels  than  for  term  and  healthy  infants.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/16
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=1109798893
ER  -