TY - CHAP M1 - Book, Section TI - Pneumocystis Pneumonia A1 - Gigliotti, Francis A1 - Hughes, Walter T. A2 - Kline, Mark W. PY - 2018 T2 - Rudolph's Pediatrics, 23e AB - Pneumocystis pneumonia (PCP) occurs almost exclusively in the severely immunocompromised host, especially patients with congenital immunodeficiency diseases, acquired immunodeficiency syndrome (AIDS), and cancer, and those who have had organ transplantation. The increasing use of biologics, such as anti–tumor necrosis factor (TNF), is now putting a new group of patients at risk for developing PCP. Once pneumonia is apparent, the fatality rate is near 100% if untreated. Effective therapeutic and prophylactic drugs are available. The causative agent is an atypical fungus known for the past decade as Pneumocystis jirovecii. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182904785 ER -