TY - CHAP M1 - Book, Section TI - Neonatal Hyperbilirubinemia A1 - Loudermilk, M. Katherine A2 - Zaoutis, Lisa B. A2 - Chiang, Vincent W. PY - 2017 T2 - Comprehensive Pediatric Hospital Medicine, 2e AB - Kernicterus, or chronic bilirubin encephalopathy, is a permanent and devastating condition associated with significant mortality, morbidity, and intellectual disability. The risk for development of kernicterus in otherwise healthy newborns is increased with severe neonatal hyperbilirubinemia, or total serum bilirubin values >20 mg/dL.1 A systematic approach to the detection and management of hyperbilirubinemia in newborns is therefore critical for prevention. While kernicterus in the United States is a rare condition, with an estimated incidence of 1.5 per 100,000 full-term newborns, the diagnosis of hyperbilirubinemia is far more common, affecting over 15% of full-term infants and nearly 60% of preterm infants in the first 30 days of life.2 Hyperbilirubinemia is the most common neonatal condition requiring extension of the newborn hospital stay or readmission to the hospital after newborn discharge.3 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1146121271 ER -