TY - CHAP M1 - Book, Section TI - Disorders of Glycine Metabolism A1 - Van Hove, Johan L. K. A2 - Kline, Mark W. PY - 2018 T2 - Rudolph's Pediatrics, 23e AB - Formation and elimination of glycine occur through many pathways. One precursor of glycine is choline, which can be oxidized to betaine and sequentially demethylated to dimethylglycine, sarcosine, and glycine, which is finally degraded to CO2 and NH3. Different defects in glycine metabolism lead to distinct biochemical or clinical phenotypes. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/14 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182928451 ER -