TY - CHAP M1 - Book, Section TI - Anaphylaxis, Urticaria, and Angioedema A1 - Riedl, Marc A. A2 - Kline, Mark W. PY - 2018 T2 - Rudolph's Pediatrics, 23e AB - Anaphylaxis, urticaria, and angioedema frequently share a common pathophysiology in that these conditions most commonly result from immunoglobulin E (IgE)-mediated mast cell activation, resulting in the release of histamine, leukotrienes, and other mast cell mediators. Urticaria and angioedema are isolated to mucocutaneous symptoms, whereas anaphylaxis is an acute systemic reaction that may rapidly lead to cardiopulmonary collapse. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/05 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182931856 ER -