TY - CHAP M1 - Book, Section TI - Diagnostic Testing in Rheumatology A1 - Nigrovic, Peter A. A2 - Kline, Mark W. PY - 2018 T2 - Rudolph's Pediatrics, 23e AB - Laboratory and imaging studies rarely establish a definitive diagnosis of rheumatologic diseases in children. The prevalence of rheumatic diseases in childhood is low, and even very specific tests generate high false-positive rates unless there is a well-founded clinical suspicion for a particular illness based on an informed differential diagnosis guided by the history and physical exam. Further, the utility of an assay will vary with the nature and stage of the illness. Nonetheless, diagnostic testing can provide information that is essential for the evaluation and treatment of children with rheumatic diseases. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182932146 ER -