TY  - CHAP
M1  - Book, Section
TI  - Disorders of Amino Acid Transport Across Cell Membranes
A1  - Näntö-Salonen, Kirsti
A1  - Niinikoski, Harri
A1  - Schiff, Manuel
A2  - Kline, Mark W.
PY  - 2018
T2  - Rudolph's Pediatrics, 23e
AB  - Epithelial  cells  in  renal  tubules  and  intestinal  mucosa  use  several  different  transport  systems  to  move  amino  acids  through  the  luminal  (apical)  and  the  antiluminal  (basolateral)  membranes  of  the  cell,  using  sodium-dependent  symporters,  proton-motive  forces,  and  concentration  gradients  of  other  amino  acids.  Each  transporter  system  prefers  groups  of  amino  acids  with  certain  physicochemical  properties,  but  most  individual  amino  acids  can  use  more  than  1  transporter.  The  transport  activities  have  been  classified  into  5  main  groups:  (1)  the  “basic  system”  for  cystine  and  the  structurally  related  dibasic  cationic  amino  acids  lysine,  arginine,  and  ornithine;  (2)  the  “neutral  system”  for  neutral  amino  acids;  (3)  the  “acidic  system”  for  glutamate  and  aspartate;  (4)  the  “iminoglycine  system”  for  proline,  hydroxyproline,  and  glycine;  and  (5)  the  “β-amino  acid  system.”  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=1182928714
ER  -