TY - CHAP M1 - Book, Section TI - Free-Living Amebic Infections A1 - Mirza, Ayesha A2 - Kline, Mark W. PY - 2018 T2 - Rudolph's Pediatrics, 23e AB - Organisms of the genera Naegleria, Acanthamoeba, and Balamuthia, also known as “free-living” amebae, are known to cause meningoencephalitis in humans. Another free-living ameba genus, Sappinia, has been isolated from animals but is rarely isolated from humans. Naegleria fowleri typically causes primary amebic meningoencephalitis (PAM), which is usually fulminant in nature, whereas infections caused by Acanthamoeba and Balamuthiamandrillaris tend to be more indolent. Like Naegleria, they primarily affect the central nervous system (CNS) causing granulomatous amebic encephalitis (GAE). Several species of Acanthamoeba abound and, besides GAE, are also known to cause amebic keratitis. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/11 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182904529 ER -