TY - CHAP M1 - Book, Section TI - Germ Cell Tumors A1 - Shaikh, Furqan A1 - Halliday, Gail A1 - Frazier, A. Lindsay A2 - Kline, Mark W. PY - 2018 T2 - Rudolph's Pediatrics, 23e AB - Germ cell tumors (GCTs), a heterogeneous group of tumors that originate from the primordial germ cell (PGC), can present across a wide range of ages, sites, histologies, and clinical behaviors. GCTs can be malignant (eg, yolk sac tumors [YSTs], embryonal carcinomas, choriocarcinomas, and seminomas/germinomas) or benign (eg, teratomas and gonadoblastomas). Most children with malignant GCTs have a favorable prognosis following treatment with surgery and platinum-based chemotherapy; however, significant late effects of treatment may result. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2023/02/05 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182911594 ER -