TY - CHAP M1 - Book, Section TI - End-Stage Liver Disease A1 - Ng, Vicky Lee A2 - Kline, Mark W. PY - 2018 T2 - Rudolph's Pediatrics, 23e AB - End-stage liver disease in infants and children presents a number of medical and psychosocial challenges to the clinical care team. While many of these complications are similar to those in adults with end-stage liver disease, infants and children with end-stage liver disease have unique characteristics requiring special attention by healthcare providers. A wide variety of liver diseases may progress to cirrhosis, a final common histologic pathway characterized by diffuse fibrosis and conversion of the normal liver architecture into structurally abnormal nodules (Fig. 420-1). However, there is often a poor correlation between histology and the clinical status of the patient. Some patients with cirrhosis are essentially asymptomatic (compensated cirrhosis), whereas others have all of the sequelae of chronic liver disease (decompensated cirrhosis) discussed below. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182909324 ER -