TY - CHAP M1 - Book, Section TI - Endocrine Abnormalities Causing Growth Impairment A1 - Jeha, George S. A2 - Kline, Mark W. PY - 2018 T2 - Rudolph's Pediatrics, 23e AB - Several pituitary hormones are involved in growth and development. Pituitary hormones contribute to growth by regulating hormone secretion by peripheral glands, which act on tissues to increase growth and modulate the secretion of the pituitary itself. Growth hormone (GH) from the pituitary, thyroid hormone, and sex steroids all act synergistically at the growth plates of long bones to increase height during childhood and adolescence. Through long feedback loops, these peripheral hormones regulate the hypothalamic pituitary signals that stimulate their own release but also modulate other hypothalamic pituitary signals such as the effect of thyroid hormone on thyrotropin-releasing hormone (TRH) and thyroid-stimulating hormone (TSH) secretion as well as its effect on GH secretion. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182918851 ER -