TY - CHAP M1 - Book, Section TI - Mechanical Circulatory Support A1 - Rozenfeld, Ranna A. PY - 2018 T2 - The PICU Handbook AB - Children with severe cardiac or respiratory failure that is refractory to medical management may require mechanical cardiorespiratory support. Transient respiratory and/or circulatory support can be accomplished using extracorporeal membrane oxygenation (ECMO) (see Chapter 25), but prolonged use of ECMO is associated with increased morbidity and mortality due to the inflammation, thromboembolic complications, and issues with durability related to the oxygenator. Longer-term circulatory support without an oxygenator can be accomplished using a ventricular assist device (VAD) in patients with adequate pulmonary status. Currently, only the Berlin EXCOR is approved by the Food and Drug Administration (FDA) for pediatric use, but a number of adult VADs are being used in older children and adolescents. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1152488145 ER -