TY - CHAP M1 - Book, Section TI - Heart Transplantation A1 - Rozenfeld, Ranna A. PY - 2018 T2 - The PICU Handbook AB - Heart transplantation can be utilized in patients with end-stage heart failure that is refractory to medical and surgical management.Common indications for transplant:Cardiomyopathy requiring IV inotropes or mechanical respiratory or circulatory supportPalliated congenital heart disease with heart failure requiring IV inotropes or prostaglandin E (PGE) and/or mechanical supportPatients with heart failure due to cardiomyopathy or congenital heart disease that leads to severe limitation of exercise/activity or growthPatients with life-threatening arrhythmias untreatable with medications or an implantable defibrillatorRelative contraindications to transplant:Severe multiorgan system diseaseSevere pulmonary hypertension that is refractory to medical managementHistory of another medical condition that limits life expectancy in such a way that it would shorten graft survivalSevere psychosocial issues that may limit family's ability to care for the patient postoperatively SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1152488158 ER -