TY - CHAP M1 - Book, Section TI - Management of Acute Brain Injury A1 - Larson, Charles A1 - Guerguerian, Anne-Marie A1 - Butt, Warwick A2 - Kline, Mark W. PY - 2018 T2 - Rudolph's Pediatrics, 23e AB - Primary etiologies of acute brain injury in children include traumatic brain injury (TBI), hypoxic-ischemic encephalopathy (HIE), stroke, cerebral hemorrhages, infections, inflammatory conditions, seizures, tumor or mass lesions, metabolic abnormalities, and toxins (Table 105-1). TBI is the leading cause of death and disability in both children older than 1 year of age and young adults. Following the primary injury, the tissues surrounding the injury and the entire brain are vulnerable to further secondary injuries. The purpose of the initial management, investigation, monitoring, and treatment of acute brain injuries is aimed at preventing this secondary injury. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/18 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182925899 ER -