TY  - CHAP
M1  - Book, Section
TI  - Neonatal Jaundice
A1  - Pammi, Mohan
A1  - Lee, Henry C.
A1  - Suresh, Gautham K.
A2  - Kline, Mark W.
PY  - 2018
T2  - Rudolph's Pediatrics, 23e
AB  - Jaundice,  a  yellow  discoloration  of  the  skin  and  sclerae  resulting  from  bilirubin  deposition  in  tissues  arises  when  the  rate  of  bilirubin  production  exceeds  the  rate  of  its  elimination.  Newborn  infants  have  a  rate  of  bilirubin  formation  that  is  2  to  3  times  higher  than  that  of  adults  due  to  the  higher  hematocrit  and  the  shorter  lifespan  of  the  red  blood  cells.  The  decrease  in  bilirubin  elimination  results  from  the  limited  ability  of  the  newborn  liver  to  conjugate  bilirubin  and  the  increased  enterohepatic  circulation.  Although  jaundice  can  result  from  an  increase  in  either  unconjugated  (indirect)  or  conjugated  (direct)  bilirubin,  a  rise  in  the  indirect  fraction  is  the  most  common  cause  of  newborn  jaundice  and  is  the  focus  of  this  chapter.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/18
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=1182920783
ER  -