TY - CHAP M1 - Book, Section TI - Hypo- and Hypernatremia Abnormalities A1 - Kecskes, Susan A. A2 - Tenenbein, Milton A2 - Macias, Charles G. A2 - Sharieff, Ghazala Q. A2 - Yamamoto, Loren G. A2 - Schafermeyer, Robert PY - 2019 T2 - Strange and Schafermeyer's Pediatric Emergency Medicine, 5e AB - Sodium concentration reflects both the sodium and water contents of the body.Arginine vasopressin (AVP) is one of the primary regulatory hormones for sodium concentration. It responds to the changes in osmolality and intravascular volume to restore homeostasis to the body.Hypernatremia may result from:Primary sodium excessHypovolemic hypernatremiaHypernatremia should generally be corrected gradually to avoid the complication of cerebral edema.Aggressive treatment of hyponatremia may lead to the osmotic demyelination syndrome. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1155427927 ER -